Surgical and Oncologic Outcomes of Laparoscopic Radical Nephrectomy for Non-Metastatic Renal Cancer in Long-Term Dialysis Patients

Ther Apher Dial. 2017 Feb;21(1):31-37. doi: 10.1111/1744-9987.12500. Epub 2017 Jan 9.

Abstract

This study aimed to compare the outcomes of laparoscopic radical nephrectomy (LRN) between patients undergoing dialysis for ≤240 and >240 months. Data from all dialysis patients with non-metastatic renal cell carcinoma (RCC) treated with LRN between 2008 and 2015 in our hospital were evaluated retrospectively. Patients were divided into two groups, shorter- and longer-term dialysis patients, according to the preoperative duration of dialysis (≤240 vs. >240 months). Of 174 patients, 58 (33.3%) were on longer-term dialysis. Perioperative minor complications were significantly more frequent in the longer-term dialysis patients (P = 0.03). There was no significant difference between the two groups in other perioperative outcomes. Patients on longer-term dialysis more frequently had pathologically advanced RCC (P = 0.009) with poorer prognosis (P = 0.005). LRN for RCC in longer-term dialysis patients appears to be safe and feasible; however, careful follow-up is needed because these patients tend to have poorer prognosis.

Keywords: Complication; End-stage renal disease; Prognosis; Renal cell carcinoma; Survival.

MeSH terms

  • Carcinoma, Renal Cell / surgery*
  • Female
  • Humans
  • Kidney / surgery
  • Kidney Neoplasms / surgery*
  • Laparoscopy / methods*
  • Male
  • Middle Aged
  • Nephrectomy / methods*
  • Renal Dialysis*
  • Retrospective Studies
  • Time
  • Treatment Outcome