Participation restrictions in ambulatory amyotrophic lateral sclerosis patients: Physical and psychological factors

Muscle Nerve. 2017 Nov;56(5):912-918. doi: 10.1002/mus.25574. Epub 2017 Mar 26.

Abstract

Introduction: The aim of this study was to assess the prevalence of participation restrictions in ambulatory patients with amyotrophic lateral sclerosis (ALS) and to identify physical and psychological contributory factors.

Methods: In this cross-sectional study, self-reported participation restrictions of 72 ambulatory ALS patients were assessed using the social health status dimension (SIPSOC) of the Sickness Impact Profile (SIP-68). Associations between SIPSOC and physical functioning, psychological factors, and demographic factors were analyzed using hierarchical regression analyses.

Results: Ninety-two percent of the patients reported participation restrictions; 54.9% could be explained by physical functioning; psychological factors accounted for 8.1% of the variance. Lung capacity, functional mobility, fatigue, and helplessness were independently associated with participation restrictions.

Conclusions: Ambulatory ALS patients have participation restrictions, which may be influenced if early ALS care is directed toward lung capacity, functional mobility, fatigue, and feelings of helplessness. Muscle Nerve 56: 912-918, 2017.

Keywords: amyotrophic lateral sclerosis; fatigue; helplessness; physical functioning; psychological factors; social participation.

MeSH terms

  • Activities of Daily Living* / psychology
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Amyotrophic Lateral Sclerosis / physiopathology*
  • Amyotrophic Lateral Sclerosis / psychology*
  • Amyotrophic Lateral Sclerosis / rehabilitation
  • Cohort Studies
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Netherlands
  • Physical Examination
  • Quality of Life*
  • Self Report
  • Sickness Impact Profile
  • Statistics, Nonparametric
  • Surveys and Questionnaires
  • Vital Capacity / physiology
  • Young Adult