An in vitro model yields 'importin' new insights into chronic traumatic encephalopathy: damaged astrocytes stop 'thrombospondin' to the injury: An Editorial Highlight for 'Defective synthesis and release of astrocytic thrombospondin-1 mediates the neuronal TDP-43 proteinopathy, resulting in defects in neuronal integrity associated with chronic traumatic encephalopathy: in vitro studies'

Sausan M Jaber; Brian M Polster

doi:10.1111/jnc.13906

An in vitro model yields 'importin' new insights into chronic traumatic encephalopathy: damaged astrocytes stop 'thrombospondin' to the injury: An Editorial Highlight for 'Defective synthesis and release of astrocytic thrombospondin-1 mediates the neuronal TDP-43 proteinopathy, resulting in defects in neuronal integrity associated with chronic traumatic encephalopathy: in vitro studies'

J Neurochem. 2017 Feb;140(4):531-535. doi: 10.1111/jnc.13906. Epub 2017 Jan 10.

Authors

Sausan M Jaber^{1

2}, Brian M Polster^{1

2}

Affiliations

¹ Department of Anesthesiology, Center for Shock, Trauma and Anesthesiology Research (STAR), University of Maryland School of Medicine, Baltimore, Maryland, USA.
² Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Abstract

Read the highlighted article 'Defective synthesis and release of astrocytic thrombospondin-1 mediates the neuronal TDP-43 proteinopathy, resulting in defects in neuronal integrity associated with chronic traumatic encephalopathy: in vitro studies' on page 645.

Publication types

Editorial
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Astrocytes
Chronic Traumatic Encephalopathy
Karyopherins
TDP-43 Proteinopathies*
Thrombospondin 1*
Thrombospondins

Substances

Karyopherins
Thrombospondin 1
Thrombospondins

Abstract

Publication types

MeSH terms

Substances

Grants and funding