A laboratory assessment of the potential effect of Cry1Ab/Cry2Aj-containing Bt maize pollen on Folsomia candida by toxicological and biochemical analyses

Environ Pollut. 2017 Mar:222:94-100. doi: 10.1016/j.envpol.2016.12.079. Epub 2017 Jan 9.

Abstract

The common soil arthropod Folsomia candida can survive well when fed only maize pollen and thus may be exposed to insecticidal proteins by ingesting insect-resistant genetically engineered maize pollen containing Bacillus thuringiensis (Bt) proteins when being released into the soil. Laboratory experiments were conducted to assess the potential effects of Cry1Ab/Cry2Aj-producing transgenic Bt maize (Shuangkang 12-5) pollen on F. candida fitness. Survival, development, and the reproduction were not significantly reduced when F. candida fed on Bt maize pollen rather than on non-Bt maize pollen, but these parameters were significantly reduced when F. candida fed on non-Bt maize pollen containing the protease inhibitor E-64 at 75 μg/g pollen. The intrinsic rate of increase (rm) was not significantly reduced when F. candida fed on Bt maize pollen but was significantly reduced when F. candida fed on non-Bt maize pollen containing E-64. The activities of antioxidant-related enzymes in F. candida were not significantly affected when F. candida fed on Bt maize pollen but were significantly increased when F. candida fed on non-Bt pollen containing E-64. The results demonstrate that consumption of Bt maize pollen containing Cry1Ab/Cry2Aj has no lethal or sublethal effects on F. candida.

Keywords: Bt maize pollen; Cry1Ab/Cry2Aj; ELISA; Environmental risk assessment; Enzyme activity; Non-target effects.

MeSH terms

  • Animal Feed / adverse effects
  • Animal Feed / analysis
  • Animals
  • Arthropods / drug effects*
  • Arthropods / enzymology
  • Arthropods / metabolism
  • Bacillus thuringiensis Toxins
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism*
  • Bacterial Proteins / toxicity
  • Bacterial Toxins / genetics
  • Bacterial Toxins / metabolism
  • Bacterial Toxins / pharmacology
  • China
  • Endotoxins / genetics
  • Endotoxins / metabolism*
  • Endotoxins / toxicity
  • Hemolysin Proteins / genetics
  • Hemolysin Proteins / metabolism*
  • Hemolysin Proteins / toxicity
  • Insecticides / metabolism*
  • Insecticides / toxicity
  • Pest Control, Biological*
  • Plants, Genetically Modified / genetics
  • Plants, Genetically Modified / metabolism
  • Pollen / chemistry*
  • Protein Precursors / genetics
  • Protein Precursors / metabolism
  • Soil / chemistry
  • Zea mays*

Substances

  • Bacillus thuringiensis Toxins
  • Bacterial Proteins
  • Bacterial Toxins
  • Endotoxins
  • Hemolysin Proteins
  • Insecticides
  • Protein Precursors
  • Soil
  • insecticidal crystal protein, Bacillus Thuringiensis