Novel Mutations on EGFR Leu792 Potentially Correlate to Acquired Resistance to Osimertinib in Advanced NSCLC

J Thorac Oncol. 2017 Jun;12(6):e65-e68. doi: 10.1016/j.jtho.2016.12.024. Epub 2017 Jan 16.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Acrylamides
  • Aniline Compounds
  • Antineoplastic Agents / therapeutic use*
  • Carcinoma, Non-Small-Cell Lung / drug therapy
  • Carcinoma, Non-Small-Cell Lung / genetics*
  • Carcinoma, Non-Small-Cell Lung / pathology
  • Drug Resistance, Neoplasm / genetics*
  • ErbB Receptors / genetics*
  • Humans
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / genetics*
  • Lung Neoplasms / pathology
  • Mutation*
  • Piperazines / therapeutic use*
  • Prognosis

Substances

  • Acrylamides
  • Aniline Compounds
  • Antineoplastic Agents
  • Piperazines
  • osimertinib
  • EGFR protein, human
  • ErbB Receptors