Anti-hepatitis C virus seroprevalence in the working age population in Poland, 2004 to 2014

Euro Surveill. 2017 Jan 12;22(2):30441. doi: 10.2807/1560-7917.ES.2017.22.2.30441.

Abstract

Hepatitis C virus (HCV) infection is considered by the World Health Organization (WHO) to be a serious public health concern and one of the major public health priorities. In 2005, it was estimated that there are 185 million anti-HCV positive people in the world, which constitutes 2.8% of the global population. Our study estimates the anti-HCV seroprevalence in the working age population (15-64 years-old), mostly urban and suburban residents, in Poland from 2004 to 2014. The studied group consisted of 61,805 working-age population representatives whose data were obtained from electronic medical records of an outpatient clinic network operating on a countrywide level. Positive anti-HCV test results were obtained in 957 patients, representing 1.5% of the whole population studied throughout the analysed period. The average age of all anti-HCV positive patients was 36.8 years. Analysis of the data suggests that the proportion of anti-HCV positive patients decreased over the study period (mean positive anti-HCV = -0.0017 × year + 3.3715; R2 = 0.7558). In 2004, positive results were noted among 3.2% of patients undergoing HCV antibody tests, but in 2014, the percentage of patients with a positive result stood at 1.1%. The apparent decrease affected men and women similarly. Our study also provides evidence that screening people born before 1965 could be beneficial.

Keywords: HCV infection; anti-HCV; hepatitis C virus.

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Antibodies, Viral / blood*
  • Electronic Health Records
  • Female
  • Hepacivirus / genetics
  • Hepacivirus / isolation & purification*
  • Hepatitis C / diagnosis
  • Hepatitis C / epidemiology*
  • Humans
  • Male
  • Middle Aged
  • Poland / epidemiology
  • Population Surveillance / methods*
  • Prevalence
  • Seroepidemiologic Studies
  • Serologic Tests
  • Suburban Population
  • Urban Population
  • Young Adult

Substances

  • Antibodies, Viral