Portal vein reconstruction using vein grafts in pediatric living donor liver transplantation: Current status

Pediatr Transplant. 2017 May;21(3). doi: 10.1111/petr.12888. Epub 2017 Jan 22.

Abstract

PV reconstruction is an important aspect of LDLT, with post-transplant outcomes depending on PV reconstruction methods. However, it is unclear whether the preferential selection of these techniques is dependent on preoperative recipient characteristics. This retrospective study assessed whether preoperative recipient factors differed in pediatric patients who did and did not receive VGs for PV reconstruction. Of 113 pediatric patients who underwent LDLT from January 2010 to July 2015, 31 (27%) underwent PV reconstruction with VGs and the other 82 (73%) without VGs. The presence of collateral vessels (P<.0001) and ascites (P=.02); PV size (P<.001), thrombosis (P=.01) and the direction of flow (P=.01), Child-Pugh class A vs B/C liver function (P=.01), Alb concentration (P=.02), primary diagnosis: BA vs non-BA (P=.03), and previous abdominal surgery (P<.005) differed significantly in patients who did and did not receive VGs for PV reconstruction. PV complications, patient survival, and graft survival did not differ significantly in patients with and without VGs at 1-year follow-up. VGs should be harvested for recipients with pretransplant hypoplastic PV, intense collaterals, hepatofugal flow, poor liver status, or previous abdominal surgery.

Keywords: living donor liver transplantation; pediatric liver transplantation; portal vein reconstruction; vein graft.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Graft Survival
  • Humans
  • Infant
  • Infant, Newborn
  • Liver / surgery*
  • Liver Cirrhosis / surgery
  • Liver Transplantation / methods*
  • Living Donors
  • Male
  • Necrosis
  • Portal Vein / surgery*
  • Retrospective Studies
  • Thrombosis
  • Treatment Outcome
  • Vascular Surgical Procedures*