Weight Trajectories of Israeli Pediatric Cancer Survivors

J Pediatr Psychol. 2017 Jun 1;42(5):588-597. doi: 10.1093/jpepsy/jsw102.

Abstract

Objective: Cross-national replication of the high rates of overweight/obesity among U.S. pediatric cancer survivors (PCS) is limited. Predictors of weight trajectories of Israeli PCS were examined from diagnosis and end of active cancer treatment to 3 years posttreatment.

Methods: World Health Organization-derived body mass index (z-BMI) values were calculated at each time point from medical records of 135 Israeli PCS ( M diagnosis age = 11.4). A three-section piecewise multilevel model including age, ethnicity, gender, treatment length, and diagnosis as predictors was used to estimate z-BMI trajectories.

Results: Most participants remained at a healthy weight at all time points. Differing weight trajectories emerged for PCS diagnosed with lymphoma/leukemia versus other cancer diagnoses from diagnosis to end of treatment, but similar weight change patterns were observed posttreatment.

Conclusion: Replication of U.S. PCS weight trajectories was not observed in Israeli PCS, suggesting the importance of exploring environmental risk factors contributing to obesity among PCS.

Keywords: obesity; pediatric cancer; weight trajectory.

MeSH terms

  • Adolescent
  • Body Mass Index
  • Cancer Survivors*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Israel
  • Male
  • Models, Statistical
  • Neoplasms / complications*
  • Neoplasms / therapy
  • Overweight / diagnosis
  • Overweight / epidemiology
  • Overweight / etiology
  • Pediatric Obesity / diagnosis
  • Pediatric Obesity / epidemiology
  • Pediatric Obesity / etiology*
  • Risk Factors
  • Weight Gain*