A rare seizure: Tumor lysis syndrome after radiation therapy of a solid tumor

Sean Stuart; Jonathan Auten

doi:10.1016/j.ajem.2017.01.023

A rare seizure: Tumor lysis syndrome after radiation therapy of a solid tumor

Am J Emerg Med. 2017 Jun;35(6):941.e3-941.e4. doi: 10.1016/j.ajem.2017.01.023. Epub 2017 Jan 16.

Authors

Sean Stuart¹, Jonathan Auten²

Affiliations

¹ Emergency Department, Naval Medical Center Portsmouth, 620 John Paul Jones Circle, Portsmouth, VA 23708, United States. Electronic address: [email protected].
² Emergency Department, Naval Medical Center Portsmouth, 620 John Paul Jones Circle, Portsmouth, VA 23708, United States. Electronic address: [email protected].

PMID: 28132791
DOI: 10.1016/j.ajem.2017.01.023

Abstract

Tumor lysis syndrome (TLS) is an uncommon but life threatening condition seen in oncology patients. Due to its underlying pathophysiology, it is classically associated with hematologic malignancies following chemotherapeutic treatment. In this article, we present a case of TLS in the setting of two rare features: a solid tumor malignancy and the absence of recent chemotherapy. We briefly review risk factors and the diagnosis of this potentially fatal but treatable condition.

Keywords: Bronchogenic carcinoma; Radiotherapy; Solid tumor; Tumor lysis syndrome.

Publication types

Case Reports
Review

MeSH terms

Carcinoma, Bronchogenic / radiotherapy*
Humans
Lung Neoplasms / radiotherapy*
Lymphadenopathy / diagnostic imaging*
Male
Middle Aged
Radiography
Radiotherapy / adverse effects*
Risk Factors
Seizures / etiology*
Tumor Lysis Syndrome / etiology*