Blue Rubber Bleb Nevus Syndrome: Promising Response To Sirolimus

Indian Pediatr. 2017 Jan 15;54(1):53-54. doi: 10.1007/s13312-017-0998-1.

Abstract

Background: Blue rubber bleb nevus syndrome is a rare disease involving venous malformations.

Case characteristics: We present a 6-year-old female with the syndrome, and consumptive coagulopathy.

Intervention/outcome: After management with sirolimus, symptoms resolved.

Message: Sirolimus may be a valuable option for reducing bleeding complications and cosmetic sequelae for the patients with this syndrome.

Publication types

  • Case Reports

MeSH terms

  • Antibiotics, Antineoplastic / therapeutic use*
  • Child
  • Female
  • Gastrointestinal Neoplasms / drug therapy*
  • Gastrointestinal Neoplasms / pathology*
  • Hemangioma
  • Humans
  • Nevus, Blue / drug therapy*
  • Nevus, Blue / pathology*
  • Sirolimus / therapeutic use*
  • Skin / pathology
  • Skin Neoplasms / drug therapy*
  • Skin Neoplasms / pathology*

Substances

  • Antibiotics, Antineoplastic
  • Sirolimus

Supplementary concepts

  • Blue rubber bleb nevus syndrome