A multinational report of technical factors on stereotactic body radiotherapy for oligometastases

Future Oncol. 2017 May;13(12):1081-1089. doi: 10.2217/fon-2016-0479. Epub 2017 Feb 3.

Abstract

Aim: Oligometastatic cancer is being increasingly managed with aggressive local therapy using stereotactic body radiation therapy (SBRT). However, few guidelines exist. We summarize the results of an international survey reviewing technical factors for extracranial SBRT for oligometastatic disease to guide safe management.

Materials & methods: Seven high-volume centers contributed. Levels of agreement were categorized as strong (6-7 common responses), moderate (4-5), low (2-3) or no agreement.

Results & conclusion: We present the results of a multi-national and multi-institutional survey of technical factors of SBRT for extracranial oligometastases. Key methods including target delineation, prescription doses, normal tissue constraints, imaging and set-up for safe implementation and practice of SBRT for oligometastasis have been identified. This manuscript will serve as a foundation for future clinical evaluations.

Keywords: SBRT; oligometastatic cancer; stereotactic body radiation therapy; technical factors.

Publication types

  • Multicenter Study

MeSH terms

  • Algorithms
  • Combined Modality Therapy
  • Dose Fractionation, Radiation
  • Humans
  • Multimodal Imaging / methods
  • Neoplasm Metastasis
  • Neoplasms / diagnostic imaging
  • Neoplasms / pathology*
  • Neoplasms / radiotherapy*
  • Radiosurgery* / adverse effects
  • Radiosurgery* / methods
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted
  • Treatment Outcome
  • Tumor Burden