Comparison of low-dose coronary artery calcium scoring using low tube current technique and hybrid iterative reconstruction vs. filtered back projection

Nada Sulaiman; Jeanette Soon; Jong Kwan Park; Christopher Naoum; Shaw-Hua Kueh; Philipp Blanke; Darra Murphy; Jennifer Ellis; Cameron J Hague; Jonathon Leipsic

doi:10.1016/j.clinimag.2017.01.017

Comparison of low-dose coronary artery calcium scoring using low tube current technique and hybrid iterative reconstruction vs. filtered back projection

Clin Imaging. 2017 May-Jun:43:19-23. doi: 10.1016/j.clinimag.2017.01.017. Epub 2017 Feb 2.

Authors

Affiliations

¹ St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: [email protected].
² St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: [email protected].
³ St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: [email protected].
⁴ St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: [email protected].
⁵ St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: [email protected].
⁶ St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: [email protected].
⁷ St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: [email protected].
⁸ St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: [email protected].
⁹ St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: [email protected].
¹⁰ St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: [email protected].

PMID: 28167282
DOI: 10.1016/j.clinimag.2017.01.017

Abstract

Introduction: We sought to validate whether low dose CACS CT with hybrid IR (HIR) could replace standard dose filtered back projection (FBP).

Method: We enrolled 100 patients to undergo low dose CACS CT with HIR, in addition to routine full dose FBP.

Results: No significant difference between full and low dose CT in Agatston score 138.2±360.6 vs. 137.3±356.4 (p=0.272) or calcium mass score 19±48.3 vs. 18.7±49 (p=0.8), respectively. Bland-Altman analysis showed no systematic bias. Calcium volume difference was statistically significant 57.2±134 vs. 55.1±130.2 (p=0.001).

Conclusion: Low dose CT for calcium scoring with HIR enables stable CACS Agatston score and calcium mass quantification as compared to full dose FBP.

Keywords: Agatston score; Computed tomography; Coronary artery calcium score; Filtered back projection; Iterative reconstruction; Noise index.

Publication types

Comparative Study
Validation Study

MeSH terms

Adult
Aged
Algorithms*
Calcium / metabolism*
Coronary Artery Disease / metabolism
Coronary Artery Disease / pathology*
Coronary Vessels / metabolism
Coronary Vessels / pathology*
Female
Humans
Male
Middle Aged
Radiation Dosage
Radiographic Image Interpretation, Computer-Assisted / methods*
Radionuclide Imaging
Tomography, X-Ray Computed / methods*

Substances

Calcium