We interpreted clinical data on five eyes with preretinal macular fibrosis (macular pucker) in association with a solitary angiomalike lesion in the peripheral retina. One angioma was associated with von Hippel-Lindau disease, and the others were regarded as acquired sporadic angiomas occurring in otherwise healthy persons. Regression of the vascular mass occurred as a result of transscleral cryopexy in four eyes and by argon laser in one eye. After treatment, the macular pucker was stabilized, but regression of the preretinal membrane did not occur. The visual acuity improved after cryotherapy in one eye, and in two eyes visual improvement occurred after vitrectomy and membrane removal.