Neuromuscular manifestations of work-related myalgia in women specific to extensor carpi radialis brevis

Can J Physiol Pharmacol. 2017 Apr;95(4):404-419. doi: 10.1139/cjpp-2016-0080. Epub 2016 Nov 24.

Abstract

This study assessed neuromuscular function in the extensor carpi radialis brevis (ECRB) of female workers diagnosed with work-related myalgia (WRM, n = 14, age 45.2 ± 1.9 years) and the ECRB of healthy controls (CON, n = 10, age 34.6 ± 2.5 years). Groups were compared on voluntary and electrically evoked functional responses at rest (Pre), immediately following a 5 min repetitive task (Post-0) performed at 60% maximal voluntary contraction (MVC), and after 5 min of recovery (Post-5). Despite near complete motor unit activation (MUA) (CON 98% ± 1% vs. WRM 99% ± 1%), at Pre, WRM produced 26% less (P < 0.05) MVC force than CON. Following an MVC, twitch force was increased (P < 0.05) by 94% ± 13% and 54% ± 11% in CON and WRM, respectively (CON vs. WRM; P < 0.05). The peak force and the maximal rates of force development and decline of electrically evoked contractions (10-100 Hz) were generally depressed (P < 0.05) at Post-0 and Post-5 relative to Pre. The response pattern to increasing frequencies of stimulation was not different (P > 0.05) between groups and MUA was not impaired (CON 97% ± 1% vs. WRM 97% ± 1%; P > 0.05). In conclusion, the peripheral weakness observed in the ECRB in WRM at rest does not result in abnormal fatigue or recovery responses after performing a task controlled for relative demand (60% MVC).

Keywords: court extenseur radial du carpe; extensor carpi radialis brevis; fatigue; femmes; myalgia; myalgie; neuromusculaire; neuromuscular; travail; women; work.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Chronic Disease
  • Electromyography
  • Female
  • Forearm
  • Humans
  • Magnetic Resonance Spectroscopy
  • Middle Aged
  • Muscle Contraction / physiology*
  • Muscle Fatigue / physiology*
  • Muscle Weakness / physiopathology
  • Muscle, Skeletal / physiopathology*
  • Myalgia / physiopathology*
  • Occupational Diseases / physiopathology*