[Reference values of n-propanol elimination]

Beitr Gerichtl Med. 1989:47:385-9.
[Article in German]

Abstract

Injections of increasing doses of n-propanol provoke blood concentration curves of exponential decays with dose dependent rate constants. The n-propanol-specific clearance is approximately 10 ml/min. It is determined by a Michaelis-Menten-metabolism (max. velocity of metabolizing: approximately 2.5 mg/l min; Michaelis-Menten-constant: approximately 10 mg/l) and is inhibited in the presence of ethanol.

Publication types

  • English Abstract

MeSH terms

  • 1-Propanol / administration & dosage
  • 1-Propanol / pharmacokinetics*
  • Dose-Response Relationship, Drug
  • Female
  • Humans
  • Male
  • Metabolic Clearance Rate
  • Reference Values

Substances

  • 1-Propanol