Killer ILCs in the Fat

Emilie Narni-Mancinelli; Eric Vivier

doi:10.1016/j.immuni.2017.02.004

Killer ILCs in the Fat

Immunity. 2017 Feb 21;46(2):169-171. doi: 10.1016/j.immuni.2017.02.004.

Authors

Emilie Narni-Mancinelli¹, Eric Vivier²

Affiliations

¹ Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université, INSERM, CNRS, 13009 Marseille, France. Electronic address: [email protected].
² Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université, INSERM, CNRS, 13009 Marseille, France; Hôpital de la Timone, Assistance Publique-Hôpitaux de Marseille, 13009 Marseille, France.

PMID: 28228274
DOI: 10.1016/j.immuni.2017.02.004

Abstract

Innate lymphoid cells (ILCs) residing in adipose tissue participate in the pathogenesis of obesity, but their contribution toward adipose tissue homeostasis in the lean state is unclear. Boulenouar et al. (2017) now report that heterogenous type 1 ILCs in adipose tissues regulate macrophage homeostasis through cytotoxicity.

Publication types

Comment

MeSH terms

Adipose Tissue
Homeostasis
Humans
Immunity, Innate*
Killer Cells, Natural*
Obesity