Within-Host Sampling of a Natural Population Shows Signs of Selection on Pde1 during Bacterial Meningitis

Infect Immun. 2017 Feb 23;85(3):e01061-16. doi: 10.1128/IAI.01061-16. Print 2017 Mar.
No abstract available

Keywords: DHH family protein; bacterial meningitis; pde1; pneumococcal pathogenesis; selection.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cyclic Nucleotide Phosphodiesterases, Type 1 / genetics*
  • Cyclic Nucleotide Phosphodiesterases, Type 1 / immunology
  • Gene Frequency / genetics
  • Humans
  • Meningitis, Pneumococcal / microbiology*
  • Meningitis, Pneumococcal / prevention & control
  • Pneumococcal Vaccines / immunology
  • Silent Mutation / genetics
  • Streptococcus pneumoniae / genetics*
  • Streptococcus pneumoniae / growth & development
  • Streptococcus pneumoniae / pathogenicity*
  • Virulence / genetics

Substances

  • Pneumococcal Vaccines
  • Cyclic Nucleotide Phosphodiesterases, Type 1