Comparison of the HUI3 and the EQ-5D-3L in a nursing home setting

PLoS One. 2017 Feb 24;12(2):e0172796. doi: 10.1371/journal.pone.0172796. eCollection 2017.

Abstract

Background: Accurately assessing changes in the quality of life of older people living permanently in nursing homes is important. The multi-attribute utility instrument most commonly used and recommended to assess health-related quality of life in the nursing home population is the three-level EuroQol EQ-5D-3L. To date, there have been no studies using the Health Utilities Index Mark III (HUI3). The purpose of this study was to compare the level of agreement and sensitivity to change of the EQ-5D-3L and HUI3 in a nursing home population.

Methods: EQ-5D-3L and HUI3 scores were measured as part of a cluster randomised controlled trial of nurse led care coordination in a nursing home population in Perth, Western Australia at baseline and 6-month follow up.

Results: Both measures were completed for 199 residents at baseline and 177 at 6-month follow-up. Mean baseline utility scores for EQ-5D-3L (0.45; 95% CI 0.41-0.49) and HUI3 (0.15; 95% CI 0.10-0.20) were significantly different (Wilcoxon signed rank test, p<0.01) and agreement was poor to moderate between absolute scores from each instrument (intra-class correlation coefficient = 0.63). The EQ-5D-3L appeared more sensitive to change over the 6-month period.

Conclusion: Our findings show that the EQ-5D-3L and HUI3 estimate different utility scores among nursing home residents. These differences should be taken into account, particularly when considering the implications of the cost-effectiveness of particular interventions and we conclude that the HUI3 is no better suited to measuring health-related quality of life in a nursing home population when compared to the EQ-5D-3L.

MeSH terms

  • Activities of Daily Living
  • Aged
  • Aged, 80 and over
  • Australia
  • Cognitive Dysfunction / economics*
  • Cognitive Dysfunction / therapy
  • Female
  • Health Status Indicators
  • Health Status*
  • Humans
  • Male
  • Nursing Homes / economics*
  • Nursing Homes / standards
  • Quality of Life
  • Surveys and Questionnaires
  • Walking / economics

Grants and funding

This work was funded by the JO and JR Wicking Trust to GA. TL receives salary support as the HCF Research Foundation Postdoctoral Research Fellow. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.