The Role of Endovascular In Situ Revascularization in the Treatment of Arterial and Graft Infections

Ann Vasc Surg. 2017 Jul:42:299.e15-299.e20. doi: 10.1016/j.avsg.2016.10.044. Epub 2017 Mar 7.

Abstract

Mycotic aneurysms and prosthetic graft infections are traditionally treated with excision of the infected tissue or graft, often requiring anatomical or extraanatomical bypass, carrying significant morbidity and mortality. Currently, the role of endovascular repair without excision in this setting has yet to be defined. We present 2 case scenarios, whereby mycotic pseudoaneurysms were successfully treated with endovascular stent-graft coverage and to present an in-depth review of endovascular in situ revascularization in the treatment of arterial and graft infections. There are data to support the use of stent grafting in mycotic aortic and iliac aneurysms, lower and upper extremity native arterial infections, lower extremity prosthetic bypass infections, and infections of carotid artery aneurysms. It is our belief that this technique may be utilized as primary therapy if there is no significant contamination and certainly serves an essential role in acute rupture or hemorrhage. In situations where there is significant tissue infection, stent grafting should be considered as a bridge if traditional excision is warranted.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aneurysm, False / diagnostic imaging
  • Aneurysm, False / microbiology
  • Aneurysm, False / surgery*
  • Aneurysm, Infected / diagnostic imaging
  • Aneurysm, Infected / microbiology
  • Aneurysm, Infected / surgery*
  • Anti-Bacterial Agents / therapeutic use
  • Aortic Aneurysm, Abdominal / diagnostic imaging
  • Aortic Aneurysm, Abdominal / microbiology
  • Aortic Aneurysm, Abdominal / surgery*
  • Aortography / methods
  • Blood Vessel Prosthesis / adverse effects*
  • Blood Vessel Prosthesis Implantation / adverse effects*
  • Blood Vessel Prosthesis Implantation / instrumentation
  • Computed Tomography Angiography
  • Endovascular Procedures* / instrumentation
  • Humans
  • Male
  • Middle Aged
  • Prosthesis-Related Infections / diagnostic imaging
  • Prosthesis-Related Infections / microbiology
  • Prosthesis-Related Infections / surgery*
  • Stents
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents