Chronic Thromboembolic Pulmonary Hypertension: Pearls and Pitfalls of Diagnosis

Methodist Debakey Cardiovasc J. 2016 Oct-Dec;12(4):199-204. doi: 10.14797/mdcj-12-4-199.

Abstract

Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by chronic obstruction of major pulmonary arteries by organized thromboembolic material. Untreated CTEPH can result in pulmonary hypertension and eventually right heart failure, yet it is the only form of pulmonary hypertension that is potentially curable with surgical or catheter-based intervention. While early diagnosis is key to increasing the likelihood of successful treatment, CTEPH remains largely underdiagnosed. This article reviews the role of echocardiogram, ventilation/perfusion scan, and other available modalities in the diagnosis of CTEPH.

Keywords: chronic thromboemboli; pulmonary angiography; pulmonary hypertension; ventilation/perfusion scan.

Publication types

  • Review

MeSH terms

  • Angiography, Digital Subtraction
  • Arterial Pressure*
  • Cardiac Catheterization*
  • Chronic Disease
  • Computed Tomography Angiography
  • Diagnostic Imaging* / methods
  • Early Diagnosis
  • Echocardiography
  • Humans
  • Hypertension, Pulmonary / diagnosis*
  • Hypertension, Pulmonary / etiology
  • Hypertension, Pulmonary / physiopathology
  • Hypertension, Pulmonary / therapy
  • Magnetic Resonance Angiography
  • Perfusion Imaging
  • Predictive Value of Tests
  • Prognosis
  • Pulmonary Artery / diagnostic imaging
  • Pulmonary Artery / physiopathology*
  • Pulmonary Embolism / complications
  • Pulmonary Embolism / diagnosis*
  • Pulmonary Embolism / physiopathology
  • Pulmonary Embolism / therapy
  • Respiratory Function Tests*