Association Between Improvement in Cardiovascular Risk Profile and Changes in Sickness Absence: Results of the ICARIA Study

Rev Esp Cardiol (Engl Ed). 2017 Nov;70(11):941-951. doi: 10.1016/j.rec.2017.02.017. Epub 2017 Mar 11.
[Article in English, Spanish]

Abstract

Introduction and objectives: The purpose of this study was to investigate whether changes in cardiovascular risk (CVR) are associated with the length and cost of sickness absence.

Methods: A prospective cohort of 179 186 participants was evaluated. Each participant's CVR (SCORE) was assessed on 2 consecutive medical examinations, approximately 1 year apart (365 ± 90 days). Cardiovascular risk was categorized as < 4% or ≥ 4%, and participants were divided into 4 groups according to changes in their risk between the 2 assessments. After the second CVR estimate, a 1-year follow-up was carried out to assess sickness absence. Differences between the 4 groups in terms of the total count of sickness absence days during the follow-up period were tested using Poisson regression models.

Results: After adjustment for covariates, participants who showed an improvement in CVR had a lower count of sickness absence days compared with both those who showed a worsening in risk and those who remained stable at ≥ 4% (RR, 0.91; 95%CI, 0.84-0.98). In comparison with participants whose CVR did not improve, more of the participants whose risk did improve had quit smoking (+17.2%; P < .001), and had controlled their blood pressure (+26.0%, P < .001), total cholesterol (+9.3%; P < .001), low-density lipoprotein cholesterol (+14.9%; P < .001), and triglyceride levels (+14.6%; P < .001).

Conclusions: Our results suggest that an improvement in CVR profile is accompanied by a decrease in sickness absence during a 1-year follow-up.

Keywords: Accidente de trabajo; Baja por enfermedad; Cardiovascular disease; Cardiovascular risk; Enfermedad cardiovascular; Incapacidad temporal; Riesgo cardiovascular; Sick leave; Sickness absence; Work-related accidents.

MeSH terms

  • Absenteeism
  • Accidents, Occupational / economics
  • Accidents, Occupational / statistics & numerical data
  • Adult
  • Aged
  • Antihypertensive Agents / therapeutic use
  • Cardiovascular Diseases / economics
  • Cardiovascular Diseases / epidemiology*
  • Cholesterol, LDL / metabolism
  • Cost of Illness
  • Dyslipidemias / drug therapy
  • Dyslipidemias / economics
  • Dyslipidemias / epidemiology
  • Female
  • Humans
  • Hypertension / drug therapy
  • Hypertension / economics
  • Hypertension / epidemiology
  • Hypolipidemic Agents / therapeutic use
  • Male
  • Middle Aged
  • Occupational Diseases / economics
  • Occupational Diseases / epidemiology*
  • Prospective Studies
  • Risk Factors
  • Sick Leave / economics
  • Sick Leave / statistics & numerical data*
  • Spain / epidemiology
  • Triglycerides / metabolism

Substances

  • Antihypertensive Agents
  • Cholesterol, LDL
  • Hypolipidemic Agents
  • Triglycerides