Mandibular Reconstruction in Ameloblastoma Using Allogeneic Cord Stem Cells and Alloplastic Graft Material - Case Report

J Stem Cells. 2016;11(3):121-124.

Abstract

Ameloblastoma is a histologically benign odontogenic tumour and has a tendency of locally aggressive behaviour. This is second most prevalent odontogenic tumour and most common in the molar-ramus-angle region and surgical resection is only treatment option. In this article, we propose an innovative approach to deal with these cases by using alloplastic graft with cord stem cells. Over 2.5 years follow-up, we could demonstrate bone regeneration using this technique with no recurrence. To the best of our knowledge, this is the first report of successful regeneration of part of ramus and body of mandible using allogeneic cord stem cells in cases of Ameloblastoma.

Keywords: Allogeneic cord stem cells; Allogeneic graft material; Ameloblastoma; Mandibular reconstruction.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Ameloblastoma / diagnostic imaging
  • Ameloblastoma / pathology
  • Ameloblastoma / surgery*
  • Ameloblastoma / therapy*
  • Female
  • Fetal Blood / cytology*
  • Follow-Up Studies
  • Humans
  • Mandibular Reconstruction*
  • Osteogenesis
  • Postoperative Care
  • Radiography, Panoramic
  • Stem Cell Transplantation*
  • Stem Cells / cytology*
  • Transplantation, Homologous