Spontaneous regression of inflammatory myofibroblastic tumor of the orbit: A case report and review of literature

Orbit. 2017 Jun;36(3):178-182. doi: 10.1080/01676830.2017.1279645. Epub 2017 Mar 17.

Abstract

Inflammatory myofibroblastic tumor is a rare entity characterized by the presence of myofibroblasts and inflammatory cells within a fibrous stroma. It typically occurs in the pediatric population. The most common site of occurrence is the lung though it has been reported throughout the body. Although rare, it has been reported in the orbit. The clinical course is ill defined in the literature; here we report a case of pediatric IMT with delayed spontaneous regression.

Keywords: Orbital inflammatory myofibroblastic tumor; pseudotumor of orbit; spontaneous regression of IMT.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Actins / metabolism
  • Biomarkers, Tumor / metabolism
  • Child
  • Humans
  • Leukocyte Common Antigens / metabolism
  • Magnetic Resonance Imaging
  • Male
  • Neoplasm Proteins / metabolism
  • Neoplasm Regression, Spontaneous*
  • Neoplasms, Muscle Tissue / diagnostic imaging
  • Neoplasms, Muscle Tissue / metabolism
  • Neoplasms, Muscle Tissue / physiopathology*
  • Orbital Pseudotumor / diagnostic imaging
  • Orbital Pseudotumor / metabolism
  • Orbital Pseudotumor / physiopathology*

Substances

  • ACTA2 protein, human
  • Actins
  • Biomarkers, Tumor
  • Neoplasm Proteins
  • Leukocyte Common Antigens