Self-Administered Premedication: Improving Taxane Chemotherapy Treatment

Clin J Oncol Nurs. 2017 Apr 1;21(2):234-239. doi: 10.1188/17.CJON.234-239.

Abstract

Background: Patients receiving taxane therapy are at risk for hypersensitivity reactions without appropriate premedication management. Patients must understand the importance of taking premedications as prescribed to prevent reactions. .

Objectives: The objectives of this study were to implement and evaluate a multidisciplinary practice protocol comprised of standardized nursing documentation of premedication regimens, teaching, and patient adherence to at-home premedication in an electronic health record (EHR). .

Methods: A new process was developed to provide standardized prescriptions, a personalized instruction sheet for patients and families, and a standardized approach to document adherence and teaching in the EHR. Pre- and post-EHR audits were used twice to evaluate the practice changes. .

Findings: The findings of the first audit suggested improvement in all practice changes. After the first audit, reinforcement of the changes occurred within the group and with one-on-one meetings. The goal of 90% adherence was met at the second audit.

Keywords: electronic health records; hypersensitivity reactions; premedication; taxanes.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Antineoplastic Agents, Phytogenic / therapeutic use*
  • Breast Neoplasms / drug therapy*
  • Education, Nursing, Continuing
  • Female
  • Humans
  • Hypersensitivity / prevention & control*
  • Middle Aged
  • Premedication* / methods
  • Self Medication*
  • Taxoids / therapeutic use*

Substances

  • Antineoplastic Agents, Phytogenic
  • Taxoids