Acute Tetraplegia Caused by Rat Bite Fever in Snake Keeper and Transmission of Streptobacillus moniliformis

Emerg Infect Dis. 2017 Apr;23(4):719-721. doi: 10.3201/eid2304.161987.

Abstract

We report acute tetraplegia caused by rat bite fever in a 59-year old man (snake keeper) and transmission of Streptobacillus moniliformis. We found an identical characteristic bacterial pattern in rat and human samples, which validated genotyping-based evidence for infection with the same strain, and identified diagnostic difficulties concerning infection with this microorganism.

Keywords: France; PCR; Streptobacillus moniliformis; acute tetraplegia; bacteria; multilocus variant analysis; rat bite fever; rats; reptiles; snake keeper; snakes; species specificity; transmission; variable number tandem repeat analysis; zoonoses.

MeSH terms

  • Amoxicillin-Potassium Clavulanate Combination / therapeutic use
  • Animal Husbandry
  • Animals
  • Anti-Bacterial Agents / therapeutic use
  • Humans
  • Male
  • Middle Aged
  • Nucleic Acid Amplification Techniques
  • Quadriplegia / etiology*
  • Rat-Bite Fever / complications*
  • Rat-Bite Fever / drug therapy
  • Rats
  • Snakes
  • Streptobacillus / isolation & purification*

Substances

  • Anti-Bacterial Agents
  • Amoxicillin-Potassium Clavulanate Combination