[Choroidal metastasis from a lung adenocarcinoma treated by intravitreal injection of anti-VEGF and external beam radiotherapy: A case report]

Cancer Radiother. 2017 Apr;21(2):130-133. doi: 10.1016/j.canrad.2016.09.019. Epub 2017 Mar 23.
[Article in French]

Abstract

Choroidal metastases of lung cancer are very uncommon. This localization should be suspected on blurred vision and confirmed with an ophthalmological examination. Its treatment is not entirely codified. We report a case of blurred vision secondary to bilateral choroidal metastasis in a patient with choroidal metastases from a lung adenocarcinoma, treated by intravitreal anti-vascular endothelial growth factor (VEGF) injection and external beam radiotherapy. According to a literature review, we analyzed the place of the targeted treatments used alone or combined with the radiotherapy.

Keywords: Anti-VEGF; Carcinome non à petites cellules pulmonaire; Choroidal metastasis; Métastases choroïdiennes; NSCLC; Non-small cell lung cancer; Radiotherapy; Radiothérapie.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / secondary*
  • Adenocarcinoma / therapy*
  • Choroid Neoplasms / secondary*
  • Choroid Neoplasms / therapy*
  • Combined Modality Therapy
  • Female
  • Humans
  • Intravitreal Injections
  • Lung Neoplasms / pathology*
  • Middle Aged
  • Radiotherapy / methods
  • Vascular Endothelial Growth Factor A / antagonists & inhibitors*

Substances

  • Vascular Endothelial Growth Factor A