Prognostic value of 18 F-fluorodeoxyglucose positron emission tomography/computed tomography in patients with cutaneous angiosarcoma: A retrospective study of 18 cases

J Dermatol. 2017 Sep;44(9):1046-1049. doi: 10.1111/1346-8138.13839. Epub 2017 Mar 31.

Abstract

Cutaneous angiosarcoma (CAS) is a rare soft tissue sarcoma with rapid growth and poor prognosis. We retrospectively analyzed the data of 18 patients with CAS who underwent 18 F-Fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) at the initial visit to the Department of Dermatology, Okayama University Hospital from September 2006 to March 2016. In the univariate survival analysis, patients with high standardized uptake values (SUVmax ) of the primary tumor showed significantly poorer prognosis than those with low SUVmax . Early assessment of prognosis using PET/CT may predict patient survival and is useful in the selection of therapeutic strategies.

Keywords: angiosarcoma; maximum standardized uptake value; positron emission tomography; positron emission tomography/computed tomography; prognostic factor.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Fluorodeoxyglucose F18 / administration & dosage
  • Follow-Up Studies
  • Hemangiosarcoma / diagnostic imaging*
  • Hemangiosarcoma / mortality
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Positron Emission Tomography Computed Tomography / methods*
  • Prognosis
  • Radiopharmaceuticals / administration & dosage*
  • Retrospective Studies
  • Skin Neoplasms / diagnostic imaging*
  • Skin Neoplasms / mortality

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18