Risk of Clostridium difficile Infection in Hematology-Oncology Patients Colonized With Toxigenic C. difficile

Infect Control Hosp Epidemiol. 2017 Jun;38(6):718-720. doi: 10.1017/ice.2017.48. Epub 2017 Apr 11.

Abstract

The prevalence of colonization with toxigenic Clostridium difficile among patients with hematological malignancies and/or bone marrow transplant at admission to a 566-bed academic medical care center was 9.3%, and 13.3% of colonized patients developed symptomatic disease during hospitalization. This population may benefit from targeted C. difficile infection control interventions. Infect Control Hosp Epidemiol 2017;38:718-720.

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Agents / therapeutic use
  • Bone Marrow Transplantation
  • Carrier State / diagnosis*
  • Carrier State / microbiology
  • Cephalosporins / therapeutic use
  • Clostridioides difficile*
  • Enterocolitis, Pseudomembranous / diagnosis*
  • Enterocolitis, Pseudomembranous / microbiology
  • Female
  • Hematologic Neoplasms / complications*
  • Hematologic Neoplasms / drug therapy
  • Humans
  • Male
  • Middle Aged
  • Patient Admission
  • Prevalence
  • Prospective Studies
  • Risk Factors

Substances

  • Antineoplastic Agents
  • Cephalosporins