Lethal aplastic anemia caused by dual immune checkpoint blockade in metastatic melanoma

Ann Oncol. 2017 Jul 1;28(7):1672-1673. doi: 10.1093/annonc/mdx177.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anemia, Aplastic / blood
  • Anemia, Aplastic / chemically induced*
  • Anemia, Aplastic / immunology
  • Antibodies, Monoclonal
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • CTLA-4 Antigen / antagonists & inhibitors
  • CTLA-4 Antigen / immunology
  • Female
  • Humans
  • Ipilimumab / administration & dosage
  • Melanoma / blood
  • Melanoma / drug therapy*
  • Melanoma / immunology
  • Melanoma / pathology
  • Middle Aged
  • Neoplasm Metastasis
  • Nivolumab
  • Programmed Cell Death 1 Receptor / antagonists & inhibitors
  • Programmed Cell Death 1 Receptor / immunology

Substances

  • Antibodies, Monoclonal
  • CTLA-4 Antigen
  • CTLA4 protein, human
  • Ipilimumab
  • PDCD1 protein, human
  • Programmed Cell Death 1 Receptor
  • Nivolumab