Malacoplakia of the endometrium. An unusual case studied by electron microscopy and a review of the literature

Acta Pathol Jpn. 1988 Apr;38(4):531-40. doi: 10.1111/j.1440-1827.1988.tb02326.x.

Abstract

A rare case of malacoplakia (MKP) of the endometrium in an 88-year-old Japanese woman is presented. By light microscopy, typical Michaelis-Gutmann bodies (M-G bodies) could be identified. Electron microscopic findings revealed M-G bodies in various stages of development. These features suggested that M-G bodies were derived from round electron-dense granules that coalesced to form phagolysosomes. Early-stage M-G bodies were manifested as small, irregular, needle-shaped areas of calcification in phagolysosomes. The present paper reviews 6 cases of endometrial MKP, 5 of which have previously been reported in the literature, and this case being the sixth, to our knowledge.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Endometrium / pathology*
  • Female
  • Humans
  • Inclusion Bodies / ultrastructure
  • Malacoplakia / drug therapy
  • Malacoplakia / pathology*
  • Microscopy, Electron
  • Middle Aged
  • Progestins / therapeutic use

Substances

  • Progestins