The impact of a point-of-care testing device on CVD risk assessment completion in New Zealand primary-care practice: A cluster randomised controlled trial and qualitative investigation

PLoS One. 2017 Apr 19;12(4):e0174504. doi: 10.1371/journal.pone.0174504. eCollection 2017.

Abstract

Objectives: To assess the effect of a point of care (POC) device for testing lipids and HbA1c in addition to testing by community laboratory facilities (usual practice) on the completion of cardiovascular disease (CVD) risk assessments in general practice.

Methods: We conducted a pragmatic, cluster randomised controlled trial in 20 New Zealand general practices stratified by size and rurality and randomised to POC device plus usual practice or usual practice alone (controls). Patients aged 35-79 years were eligible if they met national guideline criteria for CVD risk assessment. Data on CVD risk assessments were aggregated using a web-based decision support programme common to each practice. Data entered into the on-line CVD risk assessment form could be saved pending blood test results. The primary outcome was the proportion of completed CVD risk assessments. Qualitative data on practice processes for CVD risk assessment and feasibility of POC testing were collected at the end of the study by interviews and questionnaire. The POC testing was supported by a comprehensive quality assurance programme.

Results: A CVD risk assessment entry was recorded for 7421 patients in 10 POC practices and 6217 patients in 10 control practices; 99.5% of CVD risk assessments had complete data in both groups (adjusted odds ratio 1.02 [95%CI 0.61-1.69]). There were major external influences that affected the trial: including a national performance target for CVD risk assessment and changes to CVD guidelines. All practices had invested in systems and dedicated staff time to identify and follow up patients to completion. However, the POC device was viewed by most as an additional tool rather than as an opportunity to review practice work flow and leverage the immediate test results for patient education and CVD risk management discussions. Shortly after commencement, the trial was halted due to a change in the HbA1c test assay performance. The trial restarted after the manufacturing issue was rectified but this affected the end use of the device.

Conclusions: Performance incentives and external influences were more powerful modifiers of practice behaviours than the POC device in relation to CVD risk assessment completion. The promise of combining risk assessment, communication and management within one consultation was not realised. With shifts in policy focus, the utility of POC devices for patient engagement in CVD preventive care may be demonstrated if fully integrated into the clinical setting.

Trial registration: Australian New Zealand Clinical Trials Registry ACTRN12613000607774.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Cardiovascular Diseases / blood
  • Cardiovascular Diseases / diagnosis*
  • Cardiovascular Diseases / physiopathology
  • Cholesterol / blood
  • Family Practice / instrumentation*
  • Family Practice / methods
  • Female
  • Glycated Hemoglobin / metabolism
  • Humans
  • Male
  • Middle Aged
  • New Zealand
  • Point-of-Care Systems / statistics & numerical data*
  • Point-of-Care Testing / statistics & numerical data*
  • Primary Health Care / methods
  • Quality Assurance, Health Care
  • Risk Assessment
  • Rural Population
  • Surveys and Questionnaires
  • Urban Population

Substances

  • Glycated Hemoglobin A
  • hemoglobin A1c protein, human
  • Cholesterol

Grants and funding

This study was supported by funding from Roche Diagnostics International Ltd and Roche Diagnostics NZ Ltd. The funders contributed to discussions about the study design and all aspects are reported in the methods section. The funders provided the POC device, consumables and training for practices on the use of the tool. The funders had otherwise no role in the data collection, analysis, decision to publish or preparation of the manuscript. SW has a Stevenson Fellowship in Health Innovation and Quality Improvement. This sponsor had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Natasha Rafter was the recipient of a National Heart Foundation of New Zealand Research Fellowship. This sponsor had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.