Pregabalin for the treatment of neuropathic pain: a narrative review for primary care providers

Curr Med Res Opin. 2017 Aug;33(8):1353-1359. doi: 10.1080/03007995.2017.1322051. Epub 2017 Jun 9.

Abstract

Background: Neuropathic pain (NeP) is a distinct type of pain caused by damage to the nervous system itself. This often severe and chronic type of pain requires specific treatments that target the underlying pain pathophysiology.

Aim: The purpose of the current narrative review is to provide an overview of pregabalin (Lyrica 1 ) for the treatment of NeP including its effects on pain, pain-related sleep interference, and other health-related outcomes, timing of therapeutic effect, safety and tolerability, and dosing. The information provided here will help primary care providers develop more effective NeP treatment strategies.

Keywords: Pregabalin; neuropathic pain; primary care; review.

Publication types

  • Review

MeSH terms

  • Analgesics / administration & dosage
  • Analgesics / therapeutic use*
  • Humans
  • Male
  • Neuralgia / drug therapy*
  • Pregabalin / therapeutic use*
  • Primary Health Care
  • Sleep
  • Treatment Outcome

Substances

  • Analgesics
  • Pregabalin