Protective Effect of Tempol Against Hypoxia-Induced Oxidative Stress and Apoptosis in H9c2 Cells

Med Sci Monit Basic Res. 2017 Apr 21:23:159-165. doi: 10.12659/MSMBR.903764.

Authors

Linlin Jing¹, Qian Li¹, Lei He¹, Wei Sun¹, Zhengping Jia¹, Huiping Ma¹

Affiliation

¹ Department of Pharmacy, Lanzhou General Hospital, Lanzhou, Gansu, China (mainland).

Abstract

Background Material and Methods Results Conclusions.

Keywords: Apoptosis; Cell Hypoxia; Free Radical Scavengers; Oxidative Stress.

MeSH terms

Animals
Antioxidants / pharmacology
Apoptosis / drug effects
Cell Count
Cell Line
Cyclic N-Oxides / therapeutic use*
Free Radical Scavengers / metabolism
Hypoxia / metabolism
Hypoxia / therapy
Myocytes, Cardiac / drug effects*
Myocytes, Cardiac / metabolism
Oxidative Stress / drug effects*
Oxidative Stress / physiology
Rats
Reactive Oxygen Species / metabolism
Spin Labels

Substances

Antioxidants
Cyclic N-Oxides
Free Radical Scavengers
Reactive Oxygen Species
Spin Labels
tempol