A Method for Microencapsulation of Cells and a Device for Its Realization

S A Lepekhova; O A Goldberg; A A Kravchenko; A E Batraks; E V Koval; I S Kurgansky; K A Apartsin

doi:10.1007/s10517-017-3721-2

A Method for Microencapsulation of Cells and a Device for Its Realization

Bull Exp Biol Med. 2017 Apr;162(6):820-823. doi: 10.1007/s10517-017-3721-2. Epub 2017 Apr 21.

Authors

S A Lepekhova^{1

2

3}, O A Goldberg⁴, A A Kravchenko⁴, A E Batraks⁴, E V Koval⁴, I S Kurgansky⁴, K A Apartsin^{4

5

6}

Affiliations

¹ Irkutsk Research Center of Surgery and Traumatology, Irkutsk, Russia. [email protected].
² Irkutsk Research Center, Siberian Division of the Russian Academy of Sciences, Irkutsk, Russia. [email protected].
³ Irkutsk State Medical University, Ministry of Health of the Russian Federation, Irkutsk, Russia. [email protected].
⁴ Irkutsk Research Center of Surgery and Traumatology, Irkutsk, Russia.
⁵ Irkutsk Research Center, Siberian Division of the Russian Academy of Sciences, Irkutsk, Russia.
⁶ Irkutsk State Medical University, Ministry of Health of the Russian Federation, Irkutsk, Russia.

PMID: 28429231
DOI: 10.1007/s10517-017-3721-2

Abstract

The device for cell encapsulation makes it possible to fabricate microcapsules of a preset size with even smooth surface, without defects or adhesion to each other, with viable cells inside the capsule. The cells were derived from newborn piglet pancreases.

Keywords: device; microcapsule; viable cells.

MeSH terms

Alginates / chemistry
Animals
Animals, Newborn
Capsules
Cells, Immobilized / cytology*
Cells, Immobilized / ultrastructure
Drug Compounding / methods*
Equipment Design
Glucuronic Acid / chemistry
Hexuronic Acids / chemistry
Humans
Islets of Langerhans / cytology*
Islets of Langerhans / ultrastructure
Pancreas / cytology*
Pancreas / ultrastructure
Swine

Substances

Alginates
Capsules
Hexuronic Acids
Glucuronic Acid