Gene and mutation independent therapy via CRISPR-Cas9 mediated cellular reprogramming in rod photoreceptors

Cell Res. 2017 Jun;27(6):830-833. doi: 10.1038/cr.2017.57. Epub 2017 Apr 21.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • CRISPR-Associated Protein 9 / metabolism*
  • CRISPR-Cas Systems / genetics*
  • Cellular Reprogramming / genetics*
  • Dependovirus / genetics
  • Genetic Therapy
  • Genetic Vectors / metabolism
  • Humans
  • Mice
  • Mutation / genetics*
  • Retinal Rod Photoreceptor Cells / metabolism*
  • Retinitis Pigmentosa / genetics
  • Retinitis Pigmentosa / therapy

Substances

  • CRISPR-Associated Protein 9