Spironolactone Metabolites in TOPCAT - New Insights into Regional Variation

N Engl J Med. 2017 Apr 27;376(17):1690-1692. doi: 10.1056/NEJMc1612601.
No abstract available

Publication types

  • Comparative Study
  • Letter

MeSH terms

  • Canada
  • Canrenone / blood*
  • Clinical Trials as Topic
  • Heart Failure / drug therapy*
  • Humans
  • Medication Adherence*
  • Mineralocorticoid Receptor Antagonists / metabolism
  • Mineralocorticoid Receptor Antagonists / therapeutic use*
  • Russia
  • Spironolactone / metabolism
  • Spironolactone / therapeutic use*
  • United States

Substances

  • Mineralocorticoid Receptor Antagonists
  • Spironolactone
  • Canrenone