Midterm results of the Ross procedure in children: an appraisal of the subannular implantation with interrupted sutures technique

Eur J Cardiothorac Surg. 2017 Oct 1;52(4):798-804. doi: 10.1093/ejcts/ezx113.

Abstract

Objectives: The support of the pulmonary autograft root by the fibromuscular left ventricular outflow tract is emphasized to address the concern related to the dilatation of the pulmonary autograft structures in the paediatric population.

Methods: This retrospective study analyses the outcomes of 75 children who were operated between 1998 and 2012 with the subannular interrupted sutures technique at a median age of 10.2 years (range, 5.3 months-18.0 years). Median follow-up time was 5.2 years (range, 3 days-13.2 years).

Results: There were no deaths, but there were 3 reinterventions on the autograft for regurgitation and 2 resections of left ventricular outflow tract obstruction. There was no significant autograft stenosis, and freedom from moderate-to-severe regurgitation was 95% (95% confidence interval: 89-100) and 88% (95% confidence interval: 77-99) at 5 and 10 years, respectively. Median z-scores at the latest follow-up examination were, at the annulus, 0.31 [interquartile range (IQR) = -0.81 to 1.2]; at the sinus of Valsalva, 2.7 (IQR = 1.5-3.5); and at the sinotubular junction, 3.1 (IQR = 1.7-4.2). The correlation between z-scores and time after the operation was negative at the level of the annulus (r = -0.29, P = 0.034) but positive at the level of the sinus (r = +0.37, P = 0.005) and the sinotubular junction (r = +0.26, P = 0.068). The median rate of change in the z-score at the annulus was low, 0.065 z-score/year (IQR = -0.13 to 0.43).

Conclusions: The subannular interrupted sutures implantation technique is associated with acceptable risks and, in the midterm, delivers limited annular dilatation, autograft regurgitation and delayed need for autograft reintervention.

Keywords: Aortic root; Congenital aortic stenosis; Left ventricular outflow tract obstruction; Ross; Subannular.

Publication types

  • Evaluation Study

MeSH terms

  • Adolescent
  • Age Factors
  • Aortic Valve / surgery
  • Aortic Valve Stenosis / congenital*
  • Aortic Valve Stenosis / diagnostic imaging
  • Aortic Valve Stenosis / surgery*
  • Autografts
  • Bioprosthesis
  • Child
  • Child, Preschool
  • Confidence Intervals
  • Cross-Sectional Studies
  • Female
  • Follow-Up Studies
  • Heart Valve Prosthesis Implantation / methods*
  • Humans
  • Infant
  • Kaplan-Meier Estimate
  • Male
  • Recovery of Function
  • Retrospective Studies
  • Risk Assessment
  • Sex Factors
  • Statistics, Nonparametric
  • Suture Techniques*
  • Time Factors
  • Treatment Outcome
  • United Kingdom
  • Ventricular Outflow Obstruction / congenital
  • Ventricular Outflow Obstruction / diagnostic imaging
  • Ventricular Outflow Obstruction / surgery*