A Road Map for Precision Cancer Medicine Using Personalized Models

Cancer Discov. 2017 May;7(5):456-458. doi: 10.1158/2159-8290.CD-17-0268.

Abstract

<b/> A study by Pauli and colleagues in this issue of Cancer Discovery describes the creation of a precision cancer platform for patients with advanced disease, integrating DNA sequencing of patient tumors with the generation of patient-derived organoids and xenografts. They propose the use of this platform for drug testing to nominate therapeutic options for individual patients and for therapeutic biomarker discovery. Cancer Discov; 7(5); 456-8. ©2017 AACRSee related article by Pauli et al., p. 462.

Publication types

  • Comment

MeSH terms

  • Heterografts
  • Humans
  • Neoplasms*
  • Organoids
  • Precision Medicine*
  • Sequence Analysis, DNA