Fecal Microbiota Transfer for Multidrug-Resistant Gram-Negatives: A Clinical Success Combined With Microbiological Failure

Open Forum Infect Dis. 2017 Mar 13;4(2):ofx047. doi: 10.1093/ofid/ofx047. eCollection 2017 Spring.

Abstract

Combined fecal microbiota transfer and antibiotic treatment prevented recurrences of urinary tract infections with multidrug-resistant (MDR) Pseudomonas aeruginosa, but it failed to eradicate intestinal colonization with MDR Escherichia coli. Based on microbiota analysis, failure was not associated with distinct diminished microbiota diversity.

Keywords: 16S analysis.; fecal microbiota transplantation; microbiome; multidrug resistance.