Structural interplay of KV7.1 and KCNE1 is essential for normal repolarization and is compromised in short QT syndrome 2 (KV7.1-A287T)

Structural interplay of K_V7.1 and KCNE1 is essential for normal repolarization and is compromised in short QT syndrome 2 (K_V7.1-A287T)

HeartRhythm Case Rep. 2016 Sep 12;2(6):521-529. doi: 10.1016/j.hrcr.2016.08.015. eCollection 2016 Nov.

¹ Institute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany.
² Human Stem Cell Pluripotency Laboratory, Max Planck Institute for Molecular Biomedicine, Münster, Germany.
³ Chemical Genomics Centre of the Max Planck Society, Dortmund, Germany.
⁴ Interdisziplinäres Zentrum für Klinische Forschung Münster (IZKF Münster) and Innovative Medizinische Forschung (IMF Münster), Faculty of Medicine, University of Münster, Münster, Germany.
⁵ Danish National Research Foundation Centre for Cardiac Arrhythmia, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.

No abstract available

Keywords: Channel; Long QT syndrome; Molecular; Short QT syndrome; Structure.