Abstract
Syphilis is associated with increased human immunodeficiency virus acquisition and sexual transmission; we examined impact on human immunodeficiency virus mother-to-child transmission among mother-infant pairs enrolled in the India Six-Week Extended-Dose Nevirapine study. Maternal syphilis, diagnosed serologically using Venereal Disease Research Laboratory titer plus Treponema Pallidum Hemagglutination Assay, was associated with 2.5-fold greater risk.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, N.I.H., Extramural
MeSH terms
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Adult
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Anti-HIV Agents / therapeutic use
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CD4 Lymphocyte Count
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Clinical Trials, Phase III as Topic
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Cost-Benefit Analysis
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Female
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Follow-Up Studies
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HIV Infections / epidemiology
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HIV Infections / transmission*
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HIV-1
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Humans
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India / epidemiology
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Infant, Newborn
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Infectious Disease Transmission, Vertical / prevention & control
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Infectious Disease Transmission, Vertical / statistics & numerical data*
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Male
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Mothers
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Nevirapine / therapeutic use
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Point-of-Care Testing* / economics
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Pregnancy
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Pregnancy Complications, Infectious / diagnosis
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Pregnancy Complications, Infectious / epidemiology*
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Prenatal Care
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Prenatal Education / organization & administration
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Randomized Controlled Trials as Topic
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Syphilis / diagnosis
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Syphilis / epidemiology*
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Syphilis Serodiagnosis* / economics
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Viral Load
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Young Adult
Substances
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Anti-HIV Agents
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Nevirapine