Pediatric Inflammatory Bowel Disease

Máire A Conrad; Joel R Rosh

doi:10.1016/j.pcl.2017.01.005

Pediatric Inflammatory Bowel Disease

Pediatr Clin North Am. 2017 Jun;64(3):577-591. doi: 10.1016/j.pcl.2017.01.005.

Authors

Máire A Conrad¹, Joel R Rosh²

Affiliations

¹ Division of Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.
² Pediatric Gastroenterology, Clinical Development and Research Affairs, Goryeb Children's Hospital/Atlantic Health, Icahn School of Medicine at Mount Sinai, 100 Madison Avenue, Morristown, NJ 07962, USA. Electronic address: [email protected].

PMID: 28502439
DOI: 10.1016/j.pcl.2017.01.005

Abstract

Inflammatory bowel disease (IBD), including Crohn disease, ulcerative colitis, and IBD-unspecified, is a chronic immune-mediated condition of the gastrointestinal tract in which the goal of treatment is to induce and maintain durable remission. In pediatrics, there is a wide spectrum of presenting symptoms, but esophagogastroduodenoscopy and colonoscopy are imperative to confirming the diagnosis. Treatment goals include achieving mucosal healing of the gastrointestinal tract, reaching growth potential, limiting medication toxicities, and optimizing quality of life for all patients.

Keywords: Adolescents; Crohn; Inflammatory bowel disease; Pediatrics; Ulcerative colitis.

Publication types

Review

MeSH terms

Adolescent
Child
Diagnosis, Differential
Disease Management
Glucocorticoids / therapeutic use
Humans
Immunologic Factors / therapeutic use
Inflammatory Bowel Diseases / diagnosis*
Inflammatory Bowel Diseases / therapy

Substances

Glucocorticoids
Immunologic Factors