Abstract
A group of spontaneously occurring animal papillomas which were negative or positive for papillomavirus group-specific antigen were examined with a battery of biotinylated lectins including Con A, WGA, succinylated-WGA, PNA and UEA-I. Canine papillomas, equine papillomas, white-tailed deer fibromas, mule deer fibromas, and bovine fibropapillomas were examined. Each lectin had a specific staining pattern. No obvious differences in staining patterns between normal skin, viral antigen-positive and -negative neoplasms were identified. This may be due to the well-differentiated and organized nature of these tumours.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Antigens, Viral / immunology
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Cattle
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Concanavalin A / metabolism
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Deer
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Dogs
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Horse Diseases / metabolism*
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Horses
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Lectins / metabolism*
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Oligosaccharides / analysis
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Oligosaccharides / metabolism
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Papilloma / metabolism
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Papilloma / veterinary*
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Papillomaviridae / immunology
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Peanut Agglutinin
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Plant Lectins*
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Skin Neoplasms / metabolism
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Skin Neoplasms / veterinary*
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Wheat Germ Agglutinins / metabolism
Substances
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Antigens, Viral
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Lectins
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Oligosaccharides
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Peanut Agglutinin
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Plant Lectins
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Ulex europaeus lectins
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Wheat Germ Agglutinins
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Concanavalin A