Intracellular-molecular changes in plasma-irradiated budding yeast cells studied using multiplex coherent anti-Stokes Raman scattering microscopy

Phys Chem Chem Phys. 2017 May 31;19(21):13438-13442. doi: 10.1039/c7cp00489c.

Abstract

Interactions between non-equilibrium atmospheric-pressure plasma (NEAPP) and living cells were examined using multiplex coherent anti-Stokes Raman scattering (CARS) microscopy. Our multiplex CARS analyses revealed that NEAPP irradiation generates short-lived radicals that induce a decrease in the mitochondrial activity of budding yeast cells.

MeSH terms

  • Cell Survival / drug effects
  • Cell Survival / radiation effects
  • Mitochondria / drug effects
  • Mitochondria / radiation effects
  • Nonlinear Optical Microscopy
  • Plasma Gases / adverse effects*
  • Plasma Gases / chemistry
  • Reactive Nitrogen Species / adverse effects
  • Reactive Oxygen Species / adverse effects
  • Saccharomyces cerevisiae / chemistry
  • Saccharomyces cerevisiae / radiation effects*
  • Ultraviolet Rays

Substances

  • Plasma Gases
  • Reactive Nitrogen Species
  • Reactive Oxygen Species