Prolonged remission of Epstein-Barr virus associated lymphoma secondary to T cell-depleted bone marrow transplantation

Bone Marrow Transplant. 1988 Nov;3(6):641-6.

Abstract

High grade non-Hodgkin's lymphoma developed 42 days after allogeneic T cell-depleted bone marrow transplantation (BMT) for idiopathic aplastic anaemia. DNA hybridization studies confirmed clonality and incorporation of Epstein-Barr virus (EBV) genome. Prolonged remission followed low dose chemotherapy, local radiotherapy and early withdrawal of cyclosporin.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anemia, Aplastic / surgery
  • Bone Marrow Transplantation*
  • DNA Probes
  • Herpesvirus 4, Human / immunology
  • Humans
  • Lymphocyte Depletion*
  • Lymphoma, Non-Hodgkin / etiology*
  • Lymphoma, Non-Hodgkin / therapy
  • Male
  • Remission Induction
  • Restriction Mapping
  • T-Lymphocytes / immunology*
  • Transplantation, Homologous
  • Tumor Virus Infections / etiology*
  • Tumor Virus Infections / therapy

Substances

  • DNA Probes