Myopathy in Pediatric Thyroid States: A Review of the Literature

Pediatr Endocrinol Rev. 2016 Dec;14(2):147-158. doi: 10.17458/PER.2016.DGC.MyopathyinPediatric.

Abstract

This review highlights the presentations of myopathy in children in both hypothyroid and hyperthyroid states with an emphasis on the pathophysiology, diagnosis and treatment. Based on our review of the literature data, myopathy should be considered in all children presenting with muscular weakness or altered muscle enzymes in the context of thyroid disease.

Keywords: Creatinine kinase; Hyperthyroid; Hypothyroid; Myopathy.

Publication types

  • Review

MeSH terms

  • Child
  • Humans
  • Hyperthyroidism / complications*
  • Hypothyroidism / complications*
  • Muscle Weakness / etiology
  • Muscle Weakness / physiopathology
  • Muscle, Skeletal / drug effects
  • Muscle, Skeletal / physiology
  • Muscular Diseases / etiology*
  • Thyroid Diseases / complications
  • Thyroid Hormones / pharmacology
  • Thyroid Hormones / physiology

Substances

  • Thyroid Hormones