Donor transmitted mutation of the ABCB11 gene and ensuing intrahepatic cholestasis of pregnancy in a liver transplant recipient

Liver Transpl. 2017 Sep;23(9):1229-1232. doi: 10.1002/lt.24776.

Authors

Tiong Yeng Lim¹, Iona Coltart¹, Pierre Foskett¹, Richard Thompson¹, Sandra Strautnieks¹, Leonie Penna², Catherine Williamson³, Rosa Miquel¹, Michael A Heneghan¹

Affiliations

¹ Institute of Liver Studies, London, United Kingdom.
² Department of Obstetrics and Gynaecology, King's College Hospital, London, United Kingdom.
³ Women's Health Academic Centre, King's College London, London, United Kingdom.

PMID: 28524363
DOI: 10.1002/lt.24776

No abstract available

Publication types

Case Reports
Letter

MeSH terms

ATP Binding Cassette Transporter, Subfamily B, Member 11 / genetics*
Adult
Biliary Atresia / surgery*
Biopsy
Cholestasis, Intrahepatic / blood
Cholestasis, Intrahepatic / diagnosis
Cholestasis, Intrahepatic / drug therapy
Cholestasis, Intrahepatic / genetics*
Female
Glucocorticoids / therapeutic use
Humans
Liver / pathology
Liver Transplantation / adverse effects*
Methylprednisolone / therapeutic use
Mutation
Pregnancy
Pregnancy Complications / blood
Pregnancy Complications / diagnosis
Pregnancy Complications / drug therapy
Pregnancy Complications / genetics*

Substances

ABCB11 protein, human
ATP Binding Cassette Transporter, Subfamily B, Member 11
Glucocorticoids
Methylprednisolone

Supplementary concepts

Intrahepatic Cholestasis of Pregnancy