Starting embryonic transcription for the first time

Nat Genet. 2017 May 26;49(6):820-821. doi: 10.1038/ng.3880.

Abstract

Three studies highlight DUX proteins as key transcription factors regulating embryonic genome activation in early mammalian development.

MeSH terms

  • Animals
  • Embryo, Mammalian / metabolism*
  • Embryonic Development / genetics*
  • Gene Expression Regulation, Developmental*
  • Homeodomain Proteins / genetics*
  • Humans
  • Transcription Factors / genetics
  • Transcription Factors / metabolism
  • Transcriptional Activation*

Substances

  • Homeodomain Proteins
  • Transcription Factors