Discordance between clinical and imaging criteria: assessment by magnetic resonance imaging of the foot of patients with rheumatoid arthritis

Rheumatol Int. 2017 Aug;37(8):1357-1364. doi: 10.1007/s00296-017-3754-x. Epub 2017 May 27.

Abstract

Evaluation of the correlation between disease activity and joint involvement was assessed by MRI in the clinically dominant foot of patients with RA. We conducted a cross-sectional descriptive study of 55 patients with RA, who were subjected to clinical evaluation and MRI assessment. Imaging of the clinically dominant foot was performed, and both the Disease Activity Score 28 (DAS28-CRP) and the Health Assessment Questionnaire-Disability Index (HAQ-DI) were measured. The majority of patients classified as in clinical remission presented some degree of inflammatory activity upon MRI evaluation. Statistical analysis demonstrated no correlation between MRI findings and clinical scores. There is evidence of disease activity on MRI of the clinically dominant foot even in patients classified as in clinical remission according to the DAS28-CRP criteria.

Keywords: DAS28-CRP; Disease activity; MRI; Rheumatoid arthritis.

MeSH terms

  • Adult
  • Aged
  • Arthritis, Rheumatoid / diagnostic imaging*
  • Arthritis, Rheumatoid / pathology*
  • Cross-Sectional Studies
  • Disability Evaluation
  • Disease Progression
  • Female
  • Foot Joints / diagnostic imaging*
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Physical Examination
  • Remission Induction
  • Severity of Illness Index
  • Surveys and Questionnaires
  • Synovitis / diagnostic imaging*
  • Synovitis / pathology*