Invasive pneumococcal infection due to serotype 15A after the pneumococcal conjugate vaccine implementation in Turkey

Ayşe Büyükcam; Hüseyin Güdücüoğlu; Kamuran Karaman; Venhar Gürbüz; Emil Aliyev; Ateş Kara; Mehmet Ceyhan

doi:10.1080/21645515.2017.1331802

Invasive pneumococcal infection due to serotype 15A after the pneumococcal conjugate vaccine implementation in Turkey

Hum Vaccin Immunother. 2017 Aug 3;13(8):1892-1894. doi: 10.1080/21645515.2017.1331802. Epub 2017 Jun 2.

Authors

Ayşe Büyükcam¹, Hüseyin Güdücüoğlu², Kamuran Karaman³, Venhar Gürbüz¹, Emil Aliyev⁴, Ateş Kara¹, Mehmet Ceyhan¹

Affiliations

¹ a Hacettepe University Faculty of Medicine , Department of Pediatrics, Unit of Infectious Diseases , Ankara , Turkey.
² b Van Yüzüncü Yıl University Faculty of Medicine , Department of Medical Microbiology , Van , Turkey.
³ c Van Yüzüncü Yıl University Faculty of Medicine , Department of Pediatrics , Van , Turkey.
⁴ d Hacettepe University Faculty of Medicine , Department of Pediatrics , Ankara , Turkey.

Abstract

Invasive pneumococcal infections among children are a serious public health problem in many countries, including Turkey. Pneumococcal conjugate vaccine has been included in Turkey's National Immunization Programme since 2009. We report the first two pediatric cases of invasive pneumococcal infection due to non-vaccine serotype 15A after pneumococcal conjugate vaccine implementation in Turkey. It is essential to monitor the countries' own local seroepidemiologic data for detecting selective pressure of non-vaccine serotypes of S. pneumonia.

Keywords: child; invasive pneumococcal infection; serotype 15A; serotype replacement.

Publication types

Case Reports

MeSH terms

Adolescent
Heptavalent Pneumococcal Conjugate Vaccine / administration & dosage
Heptavalent Pneumococcal Conjugate Vaccine / adverse effects
Humans
Immunization Programs*
Male
Pneumococcal Infections / complications
Pneumococcal Infections / diagnosis
Pneumococcal Infections / epidemiology*
Pneumococcal Infections / microbiology*
Pneumococcal Vaccines / administration & dosage*
Pneumococcal Vaccines / adverse effects
Seroepidemiologic Studies*
Serogroup
Serotyping
Streptococcus pneumoniae / classification*
Streptococcus pneumoniae / pathogenicity
Turkey / epidemiology
Vaccines, Conjugate / administration & dosage
Vaccines, Conjugate / adverse effects

Substances

Heptavalent Pneumococcal Conjugate Vaccine
Pneumococcal Vaccines
Vaccines, Conjugate